Today we want to talk about the human papilloma virus (HPV). It may not sound as exciting, but believe me it is.
To our question related to sex, some parts of the human body, human relations, the warts, the immune system and unfortunately cancer. So, we definitely are not too much information, but as better understand the issue as more correct will be your decision.
I say decision because the question that I want to discuss today is if you or someone for whom you are interested.
Should You or Someone You Care About GET the HPV Vaccine?
Let’s start with the historical context. Our story begins with the common wart which most of us have to pull a finger of the hands or feet. The warts are caused by a virus, the human papilloma virus or HPV for short.
Genital warts are located in different parts of the body and especially in our genitals By genitals referring Bay women or in the anal region and penis in men.
The bay appear at different points as a front, vagina or deeper into the cervix.
Previously, no one attached great importance to the warts.
It was known to broadcast from one to another and some did not like their appearance, but recent decades have discovered some forms of cancer, as the cervix, vagina, vulva, anal, penile, and even some forms of cancer of the throat caused by HPV.
For example, 99% of cancers of the cervix, due to HPV, as approximately 90% of anal cancers and 35% of penile cancers.
But this is not widely known is that about 75% of sexually active people up to age 50 infected with HPV. The good news is that most of the time our body fights the virus HPV HPV like any other virus. However, about 10-20% of the infection persists year.
The realization that most types of virus that cause warts are harmless, but that there are certain types of HPV that cause some types of cancer, was the starting point for new research.
The researchers reasoned that if there are vaccines for viruses like influenza or hepatitis, perhaps we could create a vaccine for HPV virus, which protect against cancers before they appear.
This is exactly what happened.
Today there are two available vaccines for HPV.
The Gardasil and the Cervarix.
There are over one hundred different types of HPV, but the two types that are responsible of 70% for cancer of the cervix are the members 16 and 18.
Types 6 and 11 are responsible for 90% of non-tumor genital warts. These are not considered hazardous, but it is the best that can happen. Gardasil, protects against four strains of HPV, that protects from simple warts, while Cervarix focused only on those two that cause cancer.
Both vaccines are administered in three separate doses over a six months period.
Vaccines for cancer! Let’s admit that is something amazing! The main objective of these vaccines is to prevent cervical cancer, the most prevalent form of cancer in females caused by HPV.
In Canada, about 1 in 150 women develop cervical cancer and about 423 women die from it each year. Globally, this translates to more than 250,000 deaths annually.
Ideally, the vaccine against HPV is to be administered before the start of sexual intercourse to prevent infection with HPV.
For this reason many school programs administer the vaccine girls at the age of 11-14 years and because the peak of infection with HPV It is within the first 5 to 10 years of sexual activity, the vaccine continues in sexually active women. Until now focused on women, But there is an emerging research about whether to vaccinate and men. The man is a major source of infection for the woman and vice versa, so the young men their first vaccination protects against HPV, secondly can prevent transmission of HIV in women.
Gay men are at higher risk of anal cancer and the HPV vaccine could protect them. The next question is how effective these vaccines.
I think it depends on how you define the word effectively. Regarding the immune response, most tests indicated almost 100% efficacy in prevention against the two types of virus causing 70% of cervical cancer.
But what about the remaining 30%? The vaccine does not protect against all types of HPV responsible for cervical cancer, why even women who are vaccinated They should continue regular screening with the Pap test.
When outside of the immune response, we examine data on by reducing the actual rates of cervical cancer and other cancers, we must understand that it can take up to 20 years to develop cervical cancer.
However, most of the HPV vaccination programs launched after 2007, which means that we do not have enough time to be able to present a real reduction in the incidence of this cancer.
The first elements, mainly from Australia and the US, show a reduction in precancerous lesions, reduced rates of genital warts as well as reduced participation in control procedures, diagnosis and treatment of cervical cancer, as re-screening with Pap test, colposcopy and biopsy.
Furthermore, administration of the vaccine in women positive to HPV, protects them from future infections.
What Are the Disadvantages of the HPV Vaccine?
Various reference systems vaccination side effects collecting reports of adverse effects of vaccinations and then analyze trends, They showed possible neurological disease, blood clots and even death.
However when these serious side effects were analyzed by specific groups They showed no apparent correlation to imply causality, which means that most likely occurred by chance or for other reasons.
However, a study in Australia showed a higher rate of anaphylaxis than usual. About 2.6 people per 100,000 population have been vaccinated. Anaphylaxis can be viewed, but it is a serious allergic reaction causing rash, swelling of the throat and low blood pressure.
It is extremely rare but monitored.
Assessment of adverse reactions They are also watching people during clinical investigations. In the case of the vaccine against HPV, this method shows that about 74% It was a reaction to the vaccine, but also the same thing happened in 64% of subjects who received the vaccine, but the placebo.
The symptoms include headache, fever, nausea in about the same percentage for those who received the vaccine or placebo.
The difference between the 2 groups were mild to moderate reactions at the injection site. About 2 in 3 people reported mild to moderate pain, redness and swelling.
These reactions, along with occasional faint It is characteristic for all injectable vaccines. Usually disappear within two days.
So far, after 10 years of clinical trials, there is no evidence that a booster dose is considered necessary.
First, let’s admit that it is somewhat strange to talk about sex, warts and cancer, but when one sees people suffering from cancer and he knows that today it is possible to prevent this cancer, I think we should put the issue of the decision on the table.
Secondly, there are advantages and disadvantages.
On the one we know that the vaccine significantly reduces the risk of cervical cancer, and vaginal cancer, vulvar, anal and genital warts.
Obviously prevention of cancer is a key priority, But an equally serious problem is the fact that many women and men, particular age to “negotiate” new love affairs, to have genital warts, can be a serious problem. So the prevention of non-tumor genital warts It is equally important. On the other hand we have a vaccine that causes pain in 4 to 5 and swelling or redness at the injection site in 1 to 4 but usually for a few days. A further disadvantage is that the vaccine is made in three installments but we do not have a full picture of how negative it is.
There is a system for monitoring the use of the vaccine to identify other critical points which we have to assess over time.
The numbers help to make decisions.
For me the two numbers that stand out are The vaccine reduces significantly below 1: 150 the possibility of cancer while the incidence of anaphylaxis is only 1 in 40,000. Other studies show even the smallest incidence of anaphylaxis, and equal to one in one million. I hope that this information will help you to make the right decision about the vaccine against HPV.
It is difficult to get someone a drug when it is healthy, but only so it is possible to prevent the disease. Ultimately the choice is yours. Let me know in the comment below your views and what you think about HPV Vaccine?